Nontypeable <i>Haemophilus influenzae</i> （NTHi） Epidemiology
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چکیده
منابع مشابه
The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi)
Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (designated as NTHi) are predominantly respiratory mucosal pathogens. NTHi is present as part of the normal microbiome in the nasopharynx, from where...
متن کاملHaemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells
Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen that resides in the upper respiratory tract and contributes to a significant burden of respiratory related diseases in children and adults. Haemophilus haemolyticus is a respiratory tract commensal that can be misidentified as NTHi due to high levels of genetic relatedness. There are reports of invasive disease from H. haemo...
متن کاملAlveolar Macrophage Phagocytosis of NTHI
Background. Interactions of nontypeable Haemophilus influenzae (NTHI) with human alveolar macrophages are implicated in the persistence of NTHI in chronic obstructive pulmonary disease (COPD). However, the immunologic mechanisms that mediate NTHI-induced macrophage responses are poorly understood. We hypothesized that immunologic responses of alveolar macrophages to NTHI are impaired in COPD. M...
متن کاملTitle: Pneumococcal phenotype and interaction with nontypeable Haemophilus influenzae as determinants of otitis media progression Running title: Otitis media progression by S. pneumoniae and NTHi
Background: Mixed-species otitis media caused by Streptococcus pneumoniae (Spn) and nontypeable Haemophilus influenzae (NTHi) is associated with complex manifestations that are less common in pneumococcal infections without NTHi. We analyzed the microbiological composition of middle ear fluid (MEF) cultures and nasopharyngeal samples obtained before PCV7/13 rollout to identify bacterial factors...
متن کاملMolecular Epidemiology of Nontypeable Haemophilus influenzae Causing Community-Acquired Pneumonia in Adults
Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen which causes a variety of respiratory infections. The objectives of the study were to determine its antimicrobial susceptibility, to characterize the β-lactam resistance, and to establish a genetic characterization of NTHi isolates. Ninety-five NTHi isolates were analyzed by pulsed field gel electrophoresis (PFGE) and multi ...
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ژورنال
عنوان ژورنال: Kansenshogaku Zasshi
سال: 2011
ISSN: 0387-5911,1884-569X
DOI: 10.11150/kansenshogakuzasshi.85.227